I.O.'s pair of super-secret agents charged with closing the organization's most mysterious cases are after three recently escaped and highly contagious biological-warfare test subjects, who have made their way across the plains and caused the deaths of an entire town! With hundreds of decomposing corpses on hand, Zach and Rocky can't hope to cover up this scientific nightmare for long, especially since the three villains have fatally infected everyone on board a 747 before escaping into the streets of ! Now it's up to the Patriots to stop them...or and then all of will be next!